Place brussels sprouts in a large bowl. Drizzle with olive oil.
Combine all ingredients for spice mix in a large bowl. Mix in into brussels sprouts and use a large spoon to toss spice mix evenly among sprouts. Mix in liquid smoke if using.
Spread brussels sprouts in one layer on a greased baking sheet.
Bake for 25 minutes. Increase oven to 450 degrees and bake for another 5 minutes, or until crispy. (You might need to check every few minutes to make sure they don't burn!)